A study of the Crabtree effect in Novikoff ascites-hepatoma cells
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چکیده
منابع مشابه
Pasteur Effect in Novikoff Ascites-hepatoma Cells.
Inhibition of fermentation or of glucose uptake in the presence ofoxygen has been observed in many forms of life and is generally referred to as the 'Pasteur effect'. In most tissues, oxidative inhibition of fermentation (ethanol or lactate production) is reflected by a parallel decrease in glucose consumption. Since certain tissues utilize lactate significantly, estimation of the Pasteur effec...
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A study of the enzymes of the glycogen pathway in Novikoff ascites hepatoma shows that glycogen synthetase has the lowest activity and that the tumour contains no high-K(m) soluble glucokinase. However, incubation of tumour cells with metabolizable sugars in vitro, or intraperitoneal administration of glucose into the tumour-bearing rat, results in glycogen accumulation by the tumour cells. Gly...
متن کاملAssociation of exogenous RNA with Novikoff hepatoma ascites cells.
RNA taken up into the cells. The 4 types of RNA used included whole cellular 4 5, 18 5, and 28 S RNA from NHAC and the very GC-rich B3 fragment enzymatically cleaved from 28 S RNA of NHAC (1 7, 37, 37). The B3 fragment, composed of approximately 550 nucleotides, was chosen because it is highly hydrogen bonded and is less susceptible to degradation by RNase. The present results show that the cel...
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در دوره های آموزش ترجمه استادان بیشتر سعی دارند دانشجویان را با انواع متون آشنا سازند، درحالی که کمتر به خطاهای مکرر آنان در متن ترجمه شده می پردازند. اهمیت تحقیق حاضر مبنی بر ارتکاب مکرر خطاهای ترجمانی حتی بعد از گذراندن دوره های تخصصی ترجمه از سوی دانشجویان است. هدف از آن تاکید بر خطاهای رایج میان دانشجویان مترجمی و کاهش این خطاها با افزایش آگاهی و هوشیاری دانشجویان از بروز آنها است.از آنجا ک...
15 صفحه اولEffect of polyenic antibiotics on Ehrlich ascites and Novikoff hepatoma cells.
The incorporation of thymidine in Novikoff hepatoma cells and Ehrlich ascites cells was severely and irreversibly inhibited by the polyenic antibiotics filipin and lucensomycin, known for their action on phospholipid-cholesterol membranes. No inhibition could be shown on regenerating liver cells or on acellular preparations from tumor cells. Despite the well-known site of action of these antibi...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1966
ISSN: 0006-2936
DOI: 10.1042/bj0990413